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ANTIDIURETIC
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Stimate Nasal Spray was voluntarily pulled from the U.S. market in July 2020. The recall was issued after routine testing found the product contained higher-than-specified amounts of desmopressin, leading to a risk of serious side effects such as hyponatremia (low sodium levels in the blood), which in severe cases can cause seizures, coma, or death. Read more about the withdrawal here. If you’re currently using this medication, talk to your healthcare provider about safe options for transitioning to a different treatment. |
Overview
Stimate was approved by the FDA to stop bleeding episodes in children and adults with mild hemophilia A or mild to moderate von Willebrand’s Disease. Stimate was also known by its drug name, desmopressin.
Stimate was an antidiuretic. It was believed that Stimate worked in cases of hemophilia by increasing levels of clotting factor in the body.
How was it given?
Prescribing information stated that Stimate was given as a nasal spray.
Side effects
The FDA-approved label for Stimate listed common side effects including headache, nausea, abdominal cramps, and vaginal pain.
Rare but serious side effects listed for Stimate included changes in blood pressure, thromboembolic events, and systemic allergic reactions.
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