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... When this happens, bleeds are harder to control.Today, several nonfactor therapies are available to help: Concizumab (Alhemo) — An antibody (immune protein) that blocks a protein that slows clotting. Emicizumab (Hemlibra) — An antibody that helps blood clot without using factor VIII. ...

... They work by restoring the balance between factors that help the blood clot and factors that prevent the blood from clotting.Concizumab-mtci (Alhemo) and marstacimab-hncq (Hympavzi) help blood clot better by blocking a protein called tissue factor pathway inhibitor, which normally slows down clotting. ...